Antibacterial activity of soluble pyridinium-type polymers.
نویسندگان
چکیده
Cross-linked poly(N-benzyl-4-vinylpyridinium halide) (designated insoluble BVP) was previously reported to capture bacterial cells alive by contact with them. The corresponding linear polymer poly(N-benzyl-4-vinylpyridinium salt) (designated soluble BVP) was found to exhibit antibacterial activity. This soluble pyridinium-type polymer showed strong antibacterial activity against gram-positive bacteria, whereas it was less active against gram-negative bacteria. The antibacterial activity of this cationic, polymeric disinfectant was considerably greater than that of the corresponding monomeric compound and was approximately equal to that of conventional disinfectants such as benzalkonium chloride and chlorohexidine.
منابع مشابه
Antibacterial/Antiviral Property and Mechanism of Dual-Functional Quaternized Pyridinium-type Copolymer
Due to the massive outbreaks of pathogen-caused diseases and the increase of drug-resistant pathogens, there is a particular interest in the development of novel disinfection agents with broad-spectrum antipathogenic activity. In the present study, water-soluble pyridinium-type polyvinylpyrrolidones with different counter anions were prepared. Structural characterization was conducted via 13C–1...
متن کاملPoly(pyridinium phenylene)s: water-soluble N-type polymers.
Poly(pyridinium phenylene) conjugated polymers are synthesized by a cross-coupling and cyclization sequence. These polyelectrolytes are freely soluble in water and display high degrees of electroactivity. When reduced (n-doped) these materials display in situ conductivities as high as 160 S/cm. The high conductivity is attributed to the planar structure that is enforced by the cyclic structures...
متن کاملEffect of herbal supplements of caraway (Carum carvi) and fenugreek (Trigonella foenum graecum) on antibacterial activity and soluble protein of mucus in Cyprinus carpio fingerlings
In this study, we investigated the effects of herbal supplements of Carum carvi and Trigonella foenum graecum on soluble protein and antibacterial activity of mucus in common carp (Cyprinus carpio) fingerlings. Fish with a mean weight of 2.457±0.057 g were divided randomly into 7 treatments (one control group and the experimental groups treated with diets that contained different percents of ca...
متن کاملAntibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail.
متن کامل
Antimicrobial and Antifungal Effects of Acid and Water-Soluble Chitosan Extracted from Indian Shrimp (Fenneropenaeus indicus) Shell
Background & Objective : Currently, efforts are underway to seek new and effective antimicrobial agents, and marine resources are potent candidates for this aim. The following study was conducted to investigate the efficacy of water-soluble and acid-soluble chitosan against some pathogenic organisms. Materials & Method s: Inhibition zone of different concentrations (5, 7.5, and 10 mg/ml) of a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Applied and environmental microbiology
دوره 54 10 شماره
صفحات -
تاریخ انتشار 1988